Jun Jie LimKavita ReginaldYee-How SayMei Hui LiuFook Tim Chew2025-09-302025-09-302025-0910.1016/j.xjidi.2025.100387https://dspace-cris.utar.edu.my/handle/123456789/11417This study demonstrates that naturally derived vitamins, estimated from whole foods in the diets of young Chinese adults from Singapore and Malaysia, are associated with atopic dermatitis (AD). Higher intake of vitamins E, K1, C, B2, and D was associated with lower odds of AD. The protective effect of vitamin C was not confounded by smoking and enhanced by higher fruit intake. These findings underscore the potential role of dietary vitamins in mitigating AD risk and support further research into whole-food-based dietary strategies for AD management. © 2025 The AuthorsenAtopic dermatitisEczemaEpidemiologyInflammatory skin diseasesPublic health researchalpha tocopherolascorbic acidphytomenadioneriboflavinvitamin DadultArticleatopic dermatitisChinesecigarette smokingcohort analysiscontrolled studycross-sectional studydietary intakedisease associationdrug effecteczemaepidemiological dataevidence based medicinefemalefood intakefruit consumptionhumanmajor clinical studyMalaysiamalemedical researchpublic healthrisk assessmentSingaporevitamin intakeyoung adultjournal-article