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Phenylethanoid Glycosides Isolated from <i>Paraboea Paniculata</i>
Journal
Natural Product Communications
ISSN
1934-578X
Date Issued
2012-06
Author(s)
Tan Hor Yue
Anthony Ho Siong Hock
Lim Chan Kiang
DOI
10.1177/1934578x1200700621
Abstract
Phytochemical studies of the leaves and rhizomes of Paraboea pa niculata (Gesneriaceae) are reported for the first time. Three phenylethanoid glycosides were isolated and characterized as 3,4-dihydroxyphenethyl-(3″- O-β-D-apiofuranosyl)- β-D-glucopyranoside, calceoralarioside E, and acteoside. These isolates exhibited weak cytotoxic activity against the K-562 cell line with a 50% of cell killing rate of 40.18 μM, 27.05 μM, and 27.24 μM, respectively. In the DPPH free radical scavenging assay, their IC<sub>50</sub> values were determined as 75.89 μM, 25.00 μM, and 26.04 μM, respectively.
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